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RESEARCH PROJECT PROPOSAL 2022
MARKET SURVEY ON ORAL HERBAL PRODUCTS
FOR AMLAPITTA IN SRI LANKA
J. V. G. D. RANJIMALIE
2016/A/3413
INSTITUTE OF INDIGENOUS MEDICINE
UNIVERSITY OF COLOMBO
2022
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CONTENTS Page No.
TITLE OF THE RESEARCH ……………………………………………………………………………………5
INTRODUCTION……………………………………………………………………………………………………..5
RESEARCH OBJECTIVES………………………………………………………………………………………7
GENERAL OBJECTIVE………………………………………………………………………………………………….. 7
SPECIFIC OBJECTIVES …………………………………………………………………………………………………. 7
LITERATURE REVIEW ………………………………………………………………………………………….7
METHODOLOGY ………………………………………………………………………………………………….10
LIMITATIONS OF STUDY…………………………………………………………………………………….10
ETHICAL CONSIDERATION………………………………………………………………………………..10
RESOURCES REQUIRED………………………………………………………………………………………11
TIME WORK PLAN……………………………………………………………………………………………….12
BUDGET…………………………………………………………………………………………………………………13
UTILIZATION OF RESULTS…………………………………………………………………………………13
REFERENCES………………………………………………………………………………………………………..14
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TITLE OF THE RESEARCH
Market survey on oral herbal products for Amlapitta in sri Lanka.
INTRODUCTION
One of most prevalent disease of the gastrointestinal tract (GIT) in the modern era is Amlapitta,
which is closely related to gastritis in modern science. It refers to the stomach lining’s
inflammatory condition. The stomach’s improper usage of hydrochloric acid (HCl) as a result
of Helicobacter pylori causes the aforementioned irritation. It is known as Acid Peptic Disorder
(APD) in modern science and Amlapitta in Ayurveda. According to the Ashtanaga Samgraha
in Ayurveda, Amlapitta caused by aggravation of pitta and partially in its drava and amla
properties. If not correctly managed, this Amlapitta disease can be bothersome and lead to
several significant issues. Gastritis occasionally causes ulcers and raises the risk of stomach
cancer. But for most people, gastritis is not serious and responds well to treatment. So, it is
crucial to understand this illness and how to treat it.
Globally, 50.8% of the populations in developing countries suffer from gastritis. (Feyisa &
Woldeamanuel, 2021) Fifty-seven Sinhalese patients were investigated for the presence
of Helicobacter pylori by PCR. A prevalence of 70.1%, with 47.5% positive for cagA, was
demonstrated. (Fernando et al., 2002) The prevalence of gastritis in the study area was 78.8%.
Specifically, 48.9% and 29.9% had acute and chronic gastritis, respectively. The study found
that low income and taking medicinal drugs was slightly significantly contributed to higher
gastritis status; however, being younger age was slightly significantly contributed to lower
gastritis status. Furthermore, the results indicated that eating spiced foods (Adjusted Odds
Ratio (AOR) = 1.508; 95% CI: 1.046, 2.174), lack of physical exercise regularly (AOR = 1.780;
95% CI: 1.001, 3.168), stress (AOR = 2.168; 95% CI: 1.379, 3.4066), and substance use (AOR
= 1.478; 95% CI: 1.093, 1.999) were significantly contributed to higher gastritis status. (Feyisa
& Woldeamanuel, 2021)
Most of the people who are suffering from Gastritis tend to get herbal products from
commercial drug market to relieve their pain. Nowadays, for fulfill this purpose many herbal
products for Amlapitta are introducing to the commercial market. Herbal products are
pharmaceuticals made from plants. These herbal products are available as tablets, capsules,
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powder, tea bags, liquid extracts. (Owens, Baergen and Puckett, 2014) The effectiveness of
medicinal plants is used to create herbal treatments for illnesses. They chose substitutes because
certain herbal plants weren’t easily accessible. The introduction of adulterates can occasionally
be harmful to the natural product. Herbal treatments are commonly used to treat medical issues,
and they can frequently be bought online without a doctor’s prescription. Due to regularly made
exaggerated claims of clinical efficacy and safety, the use of herbs is still up for debate.
Worldwide, herbal products are being used more and more for therapeutic and preventive
purposes due to the popular belief in their safety. They have developed into a vital part of the
healthcare systems in many countries due to their accessibility in health food stores and online.
However, inadequate studies on their efficacy and toxicity, along with lax availability controls,
reduce their safety. The same purity and potency requirements that apply to pharmaceuticals
do not apply to herbal products. Due to the above reasons most of the commercial herbal
products are not accurate.
Apparently, due to the hectic life style, people tend to buy products from the commercial
market. Comparatively, most people prefer to buy herbal products over synthetic products.
Most people get carried away by the outer look and feel of the product. Example: the outer
cover, easy ways of applying, how famous it is in the market etc. Therefore, gradually the focus
towards the product and what is made of and its effectively becomes less important to them.
Due to the unawareness when buying herbal products, people waste considerable amount of
money and time. But finally, they have not got good results from them.
As same as in Amlapitta disease there are various herbal products in market for Amlapitta.
Therefore, I selected this topic to study the various herbal products in commercial market for
Amlapitta, forms of herbal products and their ingredients. Due to the close relationship with
Gastritis, I take the commercial oral herbal products for Gastritis as Amlapitta. In this study, I
will study the commercial oral herbal products for Amlapitta in the market as well as in the
online websites and online platforms.
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RESEARCH OBJECTIVES
GENERAL OBJECTIVE
✓ To study on oral herbal products for Amlapitta in Sri Lankan commercial drug
market.
SPECIFIC OBJECTIVES
✓ To identify the various preparation forms of oral herbal products for Amlapitta.
✓ To identify the herbal ingredients of oral herbal products for Amlapitta.
✓ To identify the chemical ingredients of the oral herbal products for Amlapitta.
✓ To identify the most common ingredients in oral herbal products for Amlapitta.
LITERATURE REVIEW
The word Amlapitta contains two words – ‘Amla’ (Sour) and ‘Pitta’ (Gastric Juice) (Sharma,
2014) Madhava Nidana was the first work to discuss this illness as a distinct entity, followed
by Kashyapa Samhita and Bhavaprakasha. Although Acharya Charaka did not specifically
address this illness, the etiology and clinical characteristics of Raktadusti and Raktaja Roga
that he did mention are strikingly similar to those of Amlapitta. The Amlapitta and Gastrits are
related in modern science. Chronic gastritis, one of the more common disorders, affects a
sizeable portion of the world’s population, and it is becoming more common. About half of the
world’s population is thought to carry Helicobacter pylori, one of the most common causes of
gastritis. There is rising concern about the illness’s global prevalence. The fact that the disorder
is treatable is expected to raise demand for the treatment of the illness. The way that gastritis
is treated has substantially changed thanks to technological breakthroughs.
Rising rates of both acute and chronic gastritis, the spread of fast-food chains globally,
technological developments in medicine, the widespread adoption of sedentary lifestyles, and
improvements in endoscopy devices that have increased diagnostic precision are all
contributing to the growth of the global market for gastritis treatment. In addition, persons with
chronic gastritis require acid-reducing drugs for the remainder of their lives, which boosts
market demand and, as a result, market expansion. However, it is projected that pricing
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concerns and a dearth of cutting-edge medical device technologies in middle-income countries
will restrain the expansion of the market for treating gastritis.
The gastroenteritis market was estimated to be worth in future. Rising lactose intolerance
issues, NSAID use, or alcohol use vulnerabilities are more likely to increase the risk of having
gastritis. The government’s emphasis on the development of novel medications to combat
disease is the second key reason fueling expansion. The market is expanding as a result of
increased healthcare spending in various nations.
Geographically, there are four major regions that make up the gastritis market: North America,
Europe, Asia Pacific, and the Rest of the World (RoW). The market for gastroenteritis is
dominated by North America, then by Europe. The increasing prevalence of gastritis and the
rising number of people leading unhealthy lifestyles are the two main reasons propelling market
expansion in these areas. According to a published study, gastritis affects one in every 100
Americans. The gastritis market is expanding most profitably in Asia Pacific, where things are
happening very swiftly. Other factors that will contribute to the market’s growth include the
creation of multiple cutting-edge therapeutic approaches for gastritis as well as the increase in
the incidence of various viral and autoimmune diseases in the Asia-Pacific region.
Herbal medicine has been used by humans since the dawn of civilization. Due to the fact that
they offer a rich supply of medicines as an alternative treatment, using herbal products is
increasingly seen as being essential to maintaining a healthy lifestyle. Past studies on the GI
effects of plants have been numerous, but they are only applicable to particular geographical
areas or plant species.
People have used plants for medicine for a very long time, even before written history. Plant
medicines were mentioned in Chinese and Egyptian papyrus writings as early as 3,000 BC.
Traditional medical systems that make use of herbal medicines include Ayurveda and
Traditional Chinese Medicine. Native American and African indigenous societies also utilized
herbs in their healing practices. Researchers found that similar or related plants were regularly
used for the same purposes by humans all throughout the world.
A plant or plant component that is used for its flavor, aroma, or therapeutic properties is known
as an herb. A specific type of dietary supplement is an herbal remedy. Along with fresh or dried
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plants, you can buy them as tablets, capsules, powders, teas, and extracts. Herbal products are
used by people to maintain or improve their health.
There are no market survey findings about oral herbal products for Amlapitta. But there are
several review articles about herbal plants and recipes for Amlapitta. According to Ayurveda
there are so many herbal plants introduced as good for Amlapitta. Vishnukranthi, Beli, Amalaki,
Aloe vera, Cucumber, and Ginger are a few of them. Some of research findings are mentioned
below. Further investigations on fruits and roots of A. marmelos suggested gastroprotective and
antiulcer properties through its related antioxidant mechanism. The 50% ethanolic extract of
root showed dose-dependent ulcer protective activity in different chronic and acute gastric ulcer
models in rats. (Asnaashari, 2018) Ginger is another natural remedy for indigestion because it
can reduce stomach acid. (Higuera, 2019) Triphala powder is a highly efficient Ayurvedic
remedy for gastritis. Combine honey and half a gram of long pepper powder to relieve gastritis.
It is advisable to take this combination twice day.
Due to the busy lives of the people, they always try to find quick tips to fulfil their requirements.
Therefore, currently a lot of new products are being released to the market. Especially for the
disease Amlapitta there are numerous products in the local market. There’s a high trend of
people going for these new products without channeling a doctor which isn’t the best option.
By considering the above said factors I have chosen to carry a survey study on the oral herbal
products in the local market.
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METHODOLOGY
• Obtain information about the oral herbal products for Amlapitta from Ayurvedic and
Western pharmacies, supermarkets (Keels, Cargills, SPAR, LAUGFS, ARPICO), and
other sources.
Key words – Gastritis
Amlapitta
Hyperacidity
Herbal products for Gastritis
Commercial products for Gastritis
• Collect data from the online websites, marketplaces and several market platforms about
the oral herbal products for Amlapitta.
• Analyze the collected data under different criteria from the SPSS software.
➢ The various oral herbal drug preparations for Amlapitta in Sri
Lanka.
➢ Plant based ingredients in the oral herbal products for Amlapitta.
➢ Chemical ingredients in the oral herbal products for Amlapitta.
➢ The most prevalent ingredients in oral herbal preparations for
Amlapitta.
LIMITATIONS OF STUDY
Due to the limitation of time, natural products for Amlapitta in Colombo supermarkets
are similar to the other supermarkets in Sri Lanka.
ETHICAL CONSIDERATION
Ethical consideration is not required.
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RESOURCES REQUIRED
• Personal resources
Guidance of supervisor
Senior Lecturer Grade 1,
Dr. (Ms.) Y. A. U. D. Karunarathne,
BAMS(Hons), MS. Prasutitantra & Stree Roga (BHU), PhD (Colombo)
Department of Prasutitantra Kaumarabhritya,
Institute of Indigenous Medicine,
University of Colombo,
Rajagiriya.
• Institutional resources
Library of Institute of Indigenous Medicine, University of Colombo.
• Ayurvedic and Western Pharmacies, Supermarkets, online herbal products
websites and platforms.
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TIME WORK PLAN
Serial
No
Work
2022
2023
Sep
Oct
Nov
Dec
Jan
Feb
Mar
1
Selecting a
problem
2
Literature survey
3
Preparation of
project proposal
4
Data collection
5
Data recording
and Analyze
6
Preparation of the
project report
7
Preparation of
project
presentation
8
Submission of the
presentation &
report
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BUDGET
Year
Details
Cost
(LKR)
2022
Preparation of the project proposal
• Stationeries, printing, binding, etc
5000.00
Preparation of the project report
• Stationeries, printing, binding, etc
• Transport
• Miscellaneous
5000.00
2000.00
1200.00
Total
13200.00
UTILIZATION OF RESULTS
After completion of this research,
✓ To publish data about the oral herbal product for Amlapitta.
.
✓ To design the oral herbal product for Amlapitta.
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REFERENCES
Asnaashari, S. (2018) Gastroprotective effects of herbal medicines (roots), Taylor & Francis.
Available at: https://www.tandfonline.com/doi/full/10.1080/10942912.2018.1473876
(Accessed: October 29, 2022).
Fernando, N. et al. (2002) Prevalence of helicobacter pylori in Sri Lanka as determined by
PCR, Journal of clinical microbiology. American Society for Microbiology. Available at:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC120560/ (Accessed: October 29, 2022).
Feyisa, Z.T. and Woldeamanuel, B.T. (2021) Prevalence and associated risk factors of gastritis
among patients visiting Saint Paul Hospital Millennium Medical College, Addis Ababa,
Ethiopia, PloS one. Public Library of Science. Available at:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872234/ (Accessed: October 29, 2022).
Feyisa, Z.T. and Woldeamanuel, B.T. (2021) Prevalence and associated risk factors of gastritis
among patients visiting Saint Paul Hospital Millennium Medical College, Addis Ababa,
Ethiopia, PloS one. Public Library of Science. Available at:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872234/#:~:text=Globally%2C%2050.8%2
5%20of%20the%20populations,gastritis%20%5B13%2C%2014%5D. (Accessed: October 29,
2022).
Higuera, V. (2019) Home remedies for indigestion: Natural ways to treat at home, Healthline.
Healthline Media. Available at: https://www.healthline.com/health/home-remedies-forindigestion#ginger (Accessed: October 29, 2022).
Owens, C., Baergen, R. and Puckett, D. (2014). Online sources of herbal product information,
The American journal of medicine. U.S. National Library of Medicine. Available at:
https://pubmed.ncbi.nlm.nih.gov/24290486/ (Accessed: November 3, 2022).
Prof. Ajaykumar Sharma, Kayachikitsa (Part 2), ChaukhambaPublishers Varanasi no.25
Amlapitta,page.324.
